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Global NASH (Non –Alcoholics Steatohepatitis) Market: Trends, Opportunities And Forecasts (2015-2030) (By Region, By Drugs – Off Label & Special Treatment Drugs, Aramachol, Clinical Pipeline, GR-MD-02, GFT 505 Market)

Published on: Dec 2015 | From USD $2000 | Published By: AZOTH ANALYTICS | Number Of Pages: 112

Executive Summary

Progressive numbers of Liver disorders along with rise in obesity will fuel the demand for NASH Drugs

The Global NASH Market is growing at a moderate rate over last five years on account of rising number of obesity among young population. NASH (non-alcoholic steatohepatitis) is a large, un-tapped market with no FDA approved therapeutics. Antioxidants, anti-diabetic medications, anti-obesity medications and antihyper Lipidemics are some of the off-label products currently used by NASH patients. Moreover, increase in number of patients suffering from fat in liver disorder is further anticipated to boost the Global NASH market in the coming years.

According to Azoth Analytics research report, Global NASH (Non Alcoholics Steatohepatitis) Market: Trends, Opportunities and Forecasts (2015-2030) - (By Region, By Drugs Off Label & Special Treatment, Aramachol, Clinical Pipeline, GR-MD-02, GFT 505 Market), global non-alcoholic steatohepatitis drug specific market is estimated to start growing by 2020 at a CAGR of 25.56% during 2020-2030, due to the projected product launches in 2020. Surge in cycles of clinical trials and their success rate has improved the probability of industries receiving commercial approval for NASH therapeutics by the end of 2020. Additionally, the absence of efficient diagnostic technologies acts as a major hurdle for the research of NASH therapeutics. Nevertheless, the emergence of novel biomarker technologies and improvements in liver biopsy technologies are expected to bring about an evolution in the diagnosis of NASH and other fatty liver diseases. Despite of these challenges, certain key players such as Galmed Pharmaceuticals, Gilead Sciences, Novo Nordisk, Genfit, Intercept and Galectin Therapeutics are conducting extensive research on NASH therapeutics and are receiving positive results from clinical trials. But, the low diagnosis rates, low prescription rates and low treatment seeking rates continue to pose significant challenges for these emerging players. The United States, which has the highest number of research initiatives concerning NASH, holds nearly half of the global market share. The chief reason behind this growth is the high prevalence of diabetes and obesity and the growing number of people suffering with these conditions. The US has the highest number cases of NASH and other non-alcoholic fatty liver diseases.

Scope of the Report

Global NASH (Non Alcoholics Steatohepatitis) Market: Trends, Opportunities and Forecasts (2015-2030) - (By Region, By Drugs Off Label & Special Treatment Drugs, Aramachol, Clinical Pipeline, GR-MD-02, GFT 505 Market) analyses the following aspects of global Alzheimers market:
Global NASH Market Size, Share & Forecast
Segmental Analysis By off Label , By Specific Drug and By Patient
Policy & Regulatory Landscape
Changing Market Trends & Emerging Opportunities
Competitive Landscape & Strategic Recommendations

Why You Should Buy This Report?

1. To gain an in-depth understanding of NASH disease and dementia market propelling globally.
2. To identify the on-going trends and anticipated growth in the next five years
3. To help industry consultants, drug and diagnostics manufacturers, vendors and dealers align their market-centric strategies
4. To obtain research based business decision and add weight to presentations and marketing material
5. To gain competitive knowledge of leading players
6. To avail limited customization in the report without any extra charges and get research data or trends added in the report as per the buyers specific needs

1. Research Methodology

2. Executive Summary

3. Global NASH Market: An Analysis

3.1 Global NASH Market Overview
3.1.1 Global NAFLD Population
3.1.2 Global NASH Population
3.1.3 Global NASH Population, By Prevalence Rate
3.1.4 Global NASH Diagnosed Cases
3.2 Global NASH Market by Therapeutics
3.3 Global NASH Off-Label Drugs Market by Value
3.4 Global NASH Off-Label Drugs Market Share by Region
3.5 Global GFT505 Market: Sizing & Growth
3.5.1. GFT505 Estimated Valuation
3.5.2. GFT505 Market By Value
3.6. Global Aramchol Market: Sizing & Growth
3.6.1. Market Size: By Value
3.6.2. Market Size: By Patient Volume
3.7. Global GR-MD-02 Market: Sizing & Growth
3.7.1 GR-MD-02 in NASH Patients
3.7.2 GR-MD-02 Market By Value

4. Country Analysis

4.1 The US Nash Market Overview
4.1.1. The US NAFLD Population
4.1.2. THE US NASH Population
4.1.3. The US NASH Prevalence Rate
4.1.4. The US NASH Diagnosed Cases
4.1.5. The US NASH Treatment Rate

5. The US NASH Market by Therapeutics

5.1 The US NASH Off-Label Drugs Market by Value
5.2 The US NASH Specific Drugs Market by Value
5.3 The US Aramchol Market: Sizing & Growth
5.3.1. The US Aramchol Market: By Value
5.3.2. The US Aramchol Market: By Patient Volume
5.3.3. The US Aramchol Penetration Rate
5.3.4. Aramchol Cost of Treatment in the US
5.4 The US GFT505 Market by Value
5.4.1 The US GR-MD-02 Market: Sizing & Growth
5.4.2. GR-MD-02 Market By Value
5.4.3. GR-MD-02 Market by Patient Volume
5.4.4. GR-MD-02 Cost of Treatment in the US

6. Regional Analysis

6.1 Europe NASH Market Overview
6.1.1. Europe NAFLD Population
6.1.2. Europe NASH Population
6.1.3. Europe NASH Prevalence Rate
6.1.4. Europe NASH Diagnosed Cases
6.1.5. Europe NASH Treatment Rate
6.2 Europe NASH Market By Therapeutics
6.2.1. Europe NASH Off- Label Drugs Market By Value
6.2.2. Europe NASH Off- Label Drug Market Share By Region
6.2.3. Europe NASH Specific Drug Market By Value
6.3 Europe Aramchol Market: Sizing & Growth
6.3.1 Europe Aramchol Market By Value
6.3.2 Europe Aramchol Market By Patient Volume
6.3.3. Europe Aramchol Penetration Rate
6.3.4. Europe Aramchol Cost of Treatment
6.4 Europe NASH GFT 505 Market By Value

7. Country Overview

7.1. Japan NASH Market Overview
7.1.1. Japan NASH Therapeutics Market By Value.

8. Clinical Pipeline Analysis of NASH Drugs

8.1. Aramchol ( Galmed)
8.1.2. Chemical Structure
8.1.3. Clinical Timeline
8.2. GFT505 ( Genfit)
8.2.1 Chemical Structure
8.2.2 Clinical Timeline
8.2. Obeticholic acid or OCA ( Intercept)
8.2.1 Chemical Structure
8.2.2 Clinical Timeline
8.2.3. Mechanism of Action
8.3. Cenicriviroc or CVC ( Tobira Therapeutics)
8.3.1. Chemical Structure
8.3.2. Route Of Administration
8.3.3. Clinical Timeline
8.4 Cenicriviroc or CVC ( Tobira Therapeutics)
8.4.1 Chemical Structure
8.4.2 Route Of Administration
8.4.3 Clinical Timeline

9. Market Dynamics

9.1 Drivers
9.2 Challenges
9.3 Market Trends & Developments

10. Competitive Landscape

10.1 Company Profiling
10.1.1 Galmed Pharmaceuticals
10.1.2 Genfit
10.1.3 Galectin Therapeutics
10.1.4 Gilead Sciences

List of Figures

1. Global NAFLD Population; 2015-2035E (In Million)
2. Global NASH Population; 2015-2035E (In Million)
3. Global Prevalence of NASH, 2014 In Percentage
4. Global NASH (Pre- fibroctic and early- stage fibrosis) Diagnosed Cases ; 2015-2035E (In Million)
5. Global NASH Off Label Drug Market by Value ; USD Million In ( 2012-2019E)
6. Global NASH Off Label Drug Market by Region ; USD Million In ( 2012-2019E)
7. Global GFT 505 Market by Value: 2017E-2030E ( USD Billion)
8. GFT 505 Estimated Valuation: In USD Million
9. GFT505 Market by Value: 2020E- 2030E ( USD Million)
10. Aramchol Market by Value: 2021E- 2035E ( USD Million)
11. Aramchol Market by Volume: 2021E- 2035E ( in Thousand)
12. GR-MD-02 Market by Value; 2021E-2030E (US$ Million)
13. The US NAFLD Population; 2015-2035E (In Million)
14. The US NASH Population; 2015-2035E (In Million)
15. Diagnose Rate of NASH in the US; 2021E-2028E (In %)
16. Treatment Rate of NASH in the US; 2021E- 2028E IN Percentage
17. The US NASH of Label Drug Market By Value; 2012-2017E (USD Million)
18. The US NASH Market By Value; 2019-2030E (USD Billion)
19. Aramchol Sales in the US; 2021E- 2035E ( USD Million)
20. Number of Patient Receiving Aramchol Treatment in the US: 2021E- 2035E In Thousands
21. Aramchol Penetration Rate in US; 2021E 2035E
22. Aramchol Cost of Treatment in US; 2021E- 2035E In Thousands
23. GFT 505 Net Sales in the North America : 2020E- 2030E ( USD Million)
24. GR-MD-02 Sales in US: 2021E-2033E ( USD Billion )
25. Number of Patient Receiving GR-MD-02 Treatment in US: 2021E-2033E In Thousand
26. GR-MD-02 Annual Cost of Treatment in the US: 2021E-2035E In Thousands
27. Europe NAFLD Population: 2015-2035E In Million
28. Europe NASH Population: 2015-2035E ( In Million)
29. Europe NASH Pre- Firoctics & Early Fibrosis Cases: 2015-2035E In Million
30. Europe NASH Prevalence Rate In Percentage 2021E-2028E
31. Europe NASH Diagnosed Cases: 2015-2035E In Million
32. Europe Diagnosis Rate 2021E-2028E
33. Europe Treatment Rate of NASH in Europe: 2021E-2028E In Percentage
34. Europe NASH Market by Value: 2012-2019E USD Million
35. Europe Treatment Rate of NASH in Europe: 2021E-2028E In Percentage
36. Europe NASH Market By Value: 2021E-2030E USD Billion
37. Europe NASH Market by Value: 2012-2019E USD Million
38. Europe NASH Market By Value: 2021E-2030E USD Billion
39. Europe Aramchol Penetration Rate in Europe: 2021E-2035E In Percentage
40. Europe Aramchol Annual Cost Of Treatment in Europe : 2021E-2035E In Thousands
41. Europe NASH Market By Value: 2021E-2030E USD Billion
42. Japan NASH Therapeutics Market by Value: 2023E- 2030E USD Billion
43. Galmed Pharmaceuticals Share Price 25th November 2015- 25 November 2014

SECONDARY RESEARCH
Secondary Research Information is collected from a number of publicly available as well as paid databases. Public sources involve publications by different associations and governments, annual reports and statements of companies, white papers and research publications by recognized industry experts and renowned academia etc. Paid data sources include third party authentic industry databases.

PRIMARY RESEARCH
Once data collection is done through secondary research, primary interviews are conducted with different stakeholders across the value chain like manufacturers, distributors, ingredient/input suppliers, end customers and other key opinion leaders of the industry. Primary research is used both to validate the data points obtained from secondary research and to fill in the data gaps after secondary research.

MARKET ENGINEERING
The market engineering phase involves analyzing the data collected, market breakdown and forecasting. Macroeconomic indicators and bottom-up and top-down approaches are used to arrive at a complete set of data points that give way to valuable qualitative and quantitative insights. Each data point is verified by the process of data triangulation to validate the numbers and arrive at close estimates.

EXPERT VALIDATION
The market engineered data is verified and validated by a number of experts, both in-house and external.

REPORT WRITING/ PRESENTATION
After the data is curated by the mentioned highly sophisticated process, the analysts begin to write the report. Garnering insights from data and forecasts, insights are drawn to visualize the entire ecosystem in a single report.

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